Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53
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چکیده
منابع مشابه
Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53
In response to ionizing radiation (IR), cells activate a DNA damage response (DDR) pathway to re-program gene expression. Previous studies using total cellular RNA analyses have shown that the stress kinase ATM and the transcription factor p53 are integral components required for induction of IR-induced gene expression. These studies did not distinguish between changes in RNA synthesis and RNA ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep43598